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About the solution
In 2011, Jack Andraka’s uncle died of pancreatic cancer.
This type of cancer is usually fatal because it is often diagnosed in the later stages of the disease, due to the location of the pancreas, which is deep inside the abdomen, so tumors may not show up or patients may develop symptoms until they’ve grown to a large size. When looking at this problem, Jack knew that the way to go about it wouldn't be the conventional route, but trying to come up with a different approach. This is when he began researching on biomarkers and particularly a protein called mesothelin, which in a person’s blood can be a clue that the tumors exist, long before they show up in a conventional x-ray ou MRI. This protein would be able to be quantified by the standard diagnostic technique known as ELISA, or enzyme-linked immunosorbent assay, which is quite expensive and complicated, making it not as available as it should be.
With this in mind, Jack wanted to achieve the quickest and easiest way to perform this test, which would be a paper test, something similar to a pregnancy test. This lead him to develop his own paper tests for this protein, which work as the filter paper coated with microscopic tubes of carbon, have antibodies that attract the mesothelin. This compels the tubes to spread apart, and as more protein piles up, the carbon’s resistance to the flow of electricity drops, making this a very easy way to measure the presence of the mesothelin.
It wasn’t easy for Jack to convince adult researchers that his idea was worth a shot. He was rejected by 200 scientists in his quest to find someone to let him work on his project in an existing lab! Finally, a scientist at Johns Hopkins University listened, and gave him space to make his idea real.
Adapted from https://kidsdiscover.com/quick-reads/how-a-teenager-invented-a-better-te...
Get in touch with the inventor here https://twitter.com/jackandraka
DISCLAIMER: This story was written by someone who is not the author of the solution, therefore please be advised that, although it was written with the utmost respect for the innovation and the innovator, there can be some incorrect statements. If you find any errors please contact the patient Innovation team via info@patient-innovation.com or at carolina.piedade@patient-innovation.com directly.
This solution shall not include mention to the use of drugs, chemicals or biologicals (including food); invasive devices; offensive, commercial or inherently dangerous content. This solution was not medically validated. Proceed with caution! If you have any doubts, please consult with a health professional.
DISCLAIMER: This story was written by someone who is not the author of the solution, therefore please be advised that, although it was written with the utmost respect for the innovation and the innovator, there can be some incorrect statements. If you find any errors please contact the patient Innovation team via info@patient-innovation.com
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LifeBank - an interactive storage of medical details on a fully encrypted USB
Breast cancer
Large cell lung cancer
Acute leukaemia
Bone cancer
Bone cancer metastatic
Brain cancer metastatic
Pancreatic carcinoma
Metastases to stomach
Whole body
Software
Caregiving
Health care
Therapy management
Fever
Weight loss
night sweat
Shortness of breath
Chemotherapies
Chemotherapy
Chemotherapy cardiotoxicity attenuation
Chemotherapy cytokine prophylaxis
Chemotherapy extravasation management
Chemotherapy multiple agents systemic
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5602
App that could use smartphone selfies to screen for pancreatic cancer
Pancreatic carcinoma
Pancreatic calcification
Pancreatic carcinoma metastatic
Pancreatic carcinoma recurrent
Pancreatic carcinoma stage 0
Pancreatic carcinoma stage I
Pancreatic carcinoma stage II
Pancreatic carcinoma stage III
Pancreatic carcinoma stage IV
Hyperbilirubinaemia
Hyperbilirubinaemia neonatal
Inborn errors of bilirubin metabolism
Jaundice
Jaundice neonatal
Jaundice hepatocellular
Jaundice extrahepatic obstructive
Jaundice acholuric
Jaundice cholestatic
Gilbert's syndrome
Rotor's syndrome
Dubin-Johnson syndrome
Crigler-Najjar syndrome
Chronic hepatitis
Alcoholic liver disease
Cholelithiasis
Pancreatolithiasis
Chronic hepatic failure
Cholecystitis
Pancreas
Mobile app
Software
Ophthalmic camera
Yellow coloration of the eyes
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949
Cancer survivors create a children's book about the disease to destigmatize and normalize conversations about cancer
Bladder cancer
Bladder cancer recurrent
Bladder cancer stage 0, with cancer in situ
Bladder cancer stage 0, without cancer in situ
Bladder cancer stage I, with cancer in situ
Bladder cancer stage I, without cancer in situ
Bladder cancer stage II
Bladder cancer stage III
Bladder cancer stage IV
Non-Hodgkin's lymphomas NEC
Bone cancer
Bone cancer metastatic
Brain cancer metastatic
Burkitt's leukaemia
Burkitt's lymphoma
Cancer
Cancer pain
Cervix cancer metastatic
Colon cancer
Colon cancer metastatic
Colon cancer recurrent
Colorectal cancer
Endometrial cancer
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Endometrial cancer recurrent
Endometrial cancer stage 0
Endometrial cancer stage I
Endometrial cancer stage II
Endometrial cancer stage III
Endometrial cancer stage IV
Fallopian tube cancer
Follicle centre lymphoma diffuse small cell lymphoma
Gallbladder cancer
Gastric cancer
Small intestine carcinoma
Oropharyngeal cancer
Salivary gland cancer
Pancreatic carcinoma
Transitional cell cancer of renal pelvis and ureter metastatic
Transitional cell cancer of the renal pelvis and ureter
Transitional cell cancer of the renal pelvis and ureter localised
Transitional cell cancer of the renal pelvis and ureter recurrent
Transitional cell cancer of the renal pelvis and ureter regional
Transitional cell carcinoma
Genital cancer male
Genital cancer male in situ
Germ cell cancer
Germ cell cancer metastatic
Hairy cell leukaemia
Hepatic cancer
Hepatic cancer metastatic
Hepatobiliary cancer
Hodgkin's disease lymphocyte depletion stage I site unspecified
Hodgkin's disease lymphocyte depletion stage I subdiaphragm
Hodgkin's disease lymphocyte depletion stage I supradiaphragm
Hodgkin's disease stage I
Intestinal T-cell lymphoma stage I
Laryngeal cancer
Laryngeal cancer metastatic
Laryngeal cancer recurrent
Laryngeal cancer stage 0
Laryngeal cancer stage I
Laryngeal cancer stage II
Laryngeal cancer stage III
Leukaemia
Gingival cancer
Oral cavity cancer metastatic
Lung cancer
Metastasis
Metastatic gastric cancer
Nasopharyngeal cancer
Whole body
Book
Health care
Helping others
Reach
Reading
Recreation and Leisure
Social interaction
Solve problems
Stress
Tension
Fatigue
Gastrointestinal and abdominal pains (excl oral and throat)
Gastrointestinal signs and symptoms NEC
Condition aggravated
Disease complication
Organ failure
Premature ageing
Sensitivity to weather change
Terminal state
Headache
Impaired movement
lack of motivation
Pleuritic pain
Pulmonary pain
Polyp
Precancerous mucosal lesion
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Chills
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Growing pains
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Musculoskeletal discomfort
Musculoskeletal pain
Neck pain
Pain in extremity
Sensation of heaviness
Spinal pain
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Pain
Pain management
Postural instability
Chemotherapy
Chemotherapy cardiotoxicity attenuation
Chemotherapy cytokine prophylaxis
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Drug therapy
Radiotherapy
Radiotherapy to brain
Radiotherapy to kidney
Radiotherapy to lung
Radiotherapy to lymph nodes
Radiotherapy to pleura
Radiotherapy to thymus
Radiotherapy to urinary bladder
Surgery
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